Common Causes of Hair Loss in Men
Hair loss is a widespread and completely normal experience for men, but that doesn’t make it any easier—many feel caught off guard, ashamed, or unsure of why it’s happening. From the first signs of thinning to more pronounced male pattern baldness, over 80% of men encounter some form of hair loss, regardless of age or background. Embracing the changes and learning to identify the patterns of hair loss can help you better understand your body and take meaningful steps toward finding a solution that suits your needs. While genetics and aging play significant roles, other factors—such as hormonal imbalances, thyroid issues, environmental stressors, and underlying health conditions—can also contribute.
Below are some of the most common causes of hair loss in men:
- Male Pattern Baldness (Androgenetic Alopecia)
- Autoimmune Hair Loss (Alopecia Areata)
- Inflammatory Scalp Hair Loss (Lichen Planopilaris & Dissecting Cellulitis)
- Stress Induced Hair Loss (Telogen Effluvium)
- Nutritional & Micronutrient-Related Hair Loss
- Thyroid Hair Loss (Subclinical Hypo/Hyperthyroidism)
An important focal point in understanding hair growth is Fibroblast Growth Factor 5 (FGF5), a crucial regulator of the hair growth cycle. FGF5 plays a key role in signaling the transition from the growth phase (anagen) to the shedding phase (catagen). Excessive FGF5 activity has been associated with shorter hair cycles and increased hair shedding, whereas inhibiting FGF5 has been shown to prolong the growth phase. Recent research into both botanical and synthetic FGF5 inhibitors has yielded promising results, demonstrating their potential to reduce hair loss and increase the proportion of active hair follicles. Evidence from a genome-wide association study and additional clinical research further supports FGF5 as a promising target for addressing male pattern hair loss.
At évolis, we are a biotech-driven hair wellness brand that is dedicated to providing science-backed solutions for hair thinning and loss. Founded by medical biology experts, our mission is to develop effective, natural treatments that tackle male hair loss causes. In this blog, we’ll explore the most common causes of hair loss in men, what they might reveal about your overall health, and how understanding these factors can guide you toward achieving long-term hair wellness.
Understanding the Hair Growth Cycle
The Four Stages of Hair Growth
Hair growth follows a cyclic process consisting of four primary stages:
- Anagen (Growth Phase): This is the active growth stage when hair emerges from the follicle. It typically lasts between 2 to 7 years.
- Catagen (Transition Phase): A short phase, lasting about 2 to 3 weeks, during which the follicle begins to shrink.
- Telogen (Resting Phase): Spanning approximately 3 months, the hair ceases growth but remains attached to the follicle.
- Exogen (Shedding Phase): During this stage, the hair naturally detaches and falls out, paving the way for new growth.
How Hair Loss Occurs
- Hormonal Changes: Hormonal fluctuations, particularly increased levels of DHT in individuals with genetic sensitivity, can impact hair health.
- Aging: With age, the anagen (growth) phase of hair naturally shortens, resulting in finer, slower-growing hair over time.
- Chronic Stress: Prolonged stress can interfere with the hair growth cycle, causing follicles to enter the shedding (telogen) phase earlier than normal.
- Nutritional Deficiencies: Insufficient levels of nutrients such as iron, zinc, or vitamin D can weaken hair follicles and impede proper hair growth.
When the natural hair growth cycle is disrupted, even for a short time, it can result in noticeable thinning or shedding. This makes it crucial to identify and address the root cause.
Male Pattern Baldness (Androgenetic Alopecia in Men)
Male pattern baldness, also known as androgenetic alopecia, is the leading cause of hair loss in men affecting 50% of men by the age of 50 and 80% of men by the age of 70. This condition is primarily triggered by dihydrotestosterone (DHT), a powerful derivative of testosterone. Over time, DHT can cause genetically predisposed hair follicles to shrink, resulting in gradual thinning and a receding hairline. While it is a common issue, androgenetic alopecia is a hormonally driven condition rather than a simple byproduct of aging. By understanding hormonal hair loss men can begin educating themselves on its root causes and build a path for effective management.
1. How Testosterone Becomes DHT
DHT, or dihydrotestosterone, is a hormone produced from testosterone, the primary male sex hormone. This transformation occurs through the action of an enzyme called 5-alpha reductase, specifically types I and II. The conversion predominantly takes place in areas like the skin, prostate, liver, and, notably, hair follicles—particularly those on the scalp.
The body converts testosterone into DHT because this hormone is essential for the development and maintenance of male characteristics, especially during puberty and early adulthood. However, while DHT is crucial for male development, it can become problematic later in life for certain individuals. In men genetically predisposed to androgenetic alopecia, DHT plays a significant role in causing the miniaturization, or shrinking, of hair follicles on the scalp. This predisposition is typically associated with a higher concentration of androgen receptors in the hair follicles, making them more sensitive to DHT. As a result, the follicles are more susceptible to its shrinking effects, leading to hair loss.
2. DHT Interaction with Hair Follicle Receptors
When DHT attaches to androgen receptors in genetically predisposed hair follicles—mainly at the crown and hairline—it disrupts the normal timing of the hair growth cycle. This interference shortens the growth phase (anagen) while prolonging the resting (telogen) and shedding (exogen) phases. Over time, this hormonal imbalance decreases the number of actively growing hairs, leading to gradual thinning in the regions most impacted by androgenetic alopecia.
3. Miniaturization of Hair Follicles
Over time, consistent exposure to DHT initiates a cycle known as follicle miniaturization:
- The anagen (growth) phase of the hair cycle gradually shortens.
- The telogen (resting) phase becomes longer.
- Hair strands grow progressively finer, shorter, and lose pigmentation with each cycle.
- Eventually, the follicle shrinks to the point where it produces vellus-like hairs—thin, wispy strands that provide minimal to no coverage.
It's important to note that this process does not involve the death of the follicle but rather a gradual decline in its functionality.
4. Why Miniaturization Leads to Balding
The follicles gradually decrease in both size and functionality, resulting in the production of finer, shorter hairs. Over time, the growth phase of the hair cycle becomes shorter, while the resting phase lengthens. This progression leads to thinner, lighter hairs that are more prone to falling out. In more advanced stages, the follicles may cease producing hair entirely.
This occurs because miniaturization progressively diminishes the follicle’s capacity to generate visible, healthy hair. As this process advances, the hairs that do grow become increasingly thin, short, and light, eventually resembling the soft, nearly invisible “vellus” hairs commonly found on the body or face. With each growth cycle, the follicles continue to shrink until they are no longer capable of supporting hair growth. When a significant number of follicles in a specific area, such as the crown or hairline, undergo this miniaturization, it leads to the thinning and eventual loss of coverage that defines male pattern baldness.
Supporting and Protecting Hair Follicles
While androgenetic alopecia is a progressive condition, hair follicles do not cease functioning abruptly, they weaken over time. In many cases, they can still be nurtured and supported. By targeting the underlying factors that disrupt the hair growth cycle, it’s possible to prolong the growth phase, enhance scalp health, and maintain follicle activity for an extended period.
Recent research provides encouraging insights in this area. By addressing hormonal factors like DHT alongside molecular triggers such as FGF5, we can create an environment that helps follicles remain active and productive for longer. Combining these strategies offers men a more comprehensive approach to preserving existing hair and encouraging healthier regrowth.
évolis embraces this science-driven approach to hair health by focusing on the role of FGF5 in the hair growth cycle. Through carefully formulated products designed to minimize the impact of FGF5, évolis aims to extend the growth phase, giving hair follicles a better chance to stay active. Supported by clinical research, this method provides a non-invasive solution for men seeking to counteract the biological processes that lead to premature hair shedding.
Autoimmune Hair Loss in Men (Alopecia Areata)
Supporting your body and hair health can be challenging, especially when the disruption stems from your own immune system.
Alopecia areata is an autoimmune condition that leads to hair loss. It occurs when the immune system mistakenly attacks healthy hair follicles, causing them to cease hair production. This condition often manifests suddenly, resulting in round or oval patches of hair loss on the scalp. Although less common than androgenetic alopecia, alopecia areata is one of the most prevalent forms of autoimmune hair loss seen in men and can occur even in individuals without a history of hair thinning or male pattern baldness.
To better understand this condition, it’s essential to look beyond hormones and genetic hair loss, focusing instead on the intricate connection between immune system health and hair follicle function.
How the Immune System Disrupts Hair Growth
In autoimmune hair loss, the immune system mistakenly targets hair follicles, interrupting their normal function. This reaction is driven by cytokines—chemical messengers that coordinate the body’s immune response.
These cytokines initiate immune activity that can:
- Disrupt the growth phase (anagen), causing hair to shed prematurely
- Signal immune cells like T-cells to surround and impair the follicles
- Break down the follicle’s immune protection, making it more vulnerable to attack
Autoimmune Hair Loss: What Sets It Apart
What makes autoimmune hair loss unique is its unpredictability. Unlike male pattern baldness, which follows a gradual and predictable progression, autoimmune-related hair loss can arise suddenly, target any part of the scalp, and vary over time. These changes are driven by the immune system rather than hormones or aging, meaning hair may regrow on its own or fall out again unexpectedly.
Supporting Hair Health While Managing Autoimmune Conditions
Since the follicles are not destroyed, they often retain the ability to produce hair. Promoting hair health in such cases requires addressing inflammation, identifying potential immune triggers, and creating a scalp environment conducive to follicle recovery.
1. Medical Intervention
- In more advanced or persistent cases, therapies like corticosteroids, immunomodulators, or JAK inhibitors may be used to help suppress the autoimmune response and promote regrowth. Consult your healthcare provider if you are interested in these treatment options.
2. Support Inflammation Control from Within
- Incorporate an anti-inflammatory diet filled with leafy greens, healthy fats, and antioxidant-rich foods.
- Focus on promoting gut health to enhance immune function and optimize nutrient absorption.
3. Calm and Nourish the Scalp
- Choose gentle hair care products that are free from sulfates, parabens, and synthetic fragrances to minimize irritation.
- Opt for formulations containing natural anti-inflammatory botanicals like rosemary oil, mangosteen extract, or licorice root.
4. Prolong the Growth Phase with FGF5 Inhibitors
- Autoimmune-related stress may elevate FGF5 levels, which can lead to shorter hair growth cycles and slower regrowth.
- évolis products feature clinically researched botanical extracts that inhibit FGF5, helping to extend the anagen phase and encourage fuller, healthier regrowth over time.
Inflammatory Scalp Hair Loss (Lichen Planopilaris & Dissecting Cellulitis)
Not all hair loss originates in the hair follicles, sometimes, it begins at the scalp. Chronic inflammatory scalp conditions like Lichen Planopilaris (LPP) and Dissecting Cellulitis of the Scalp (DCS), though rare, are significant causes of hair loss in men. These disorders provoke intense immune responses that not only damage hair follicles but also harm the surrounding scalp tissue. This can result in scarring alopecia, where hair loss becomes permanent if left untreated.
Both LPP and DCS belong to the category of cicatricial (scarring) alopecias, where inflammation destroys hair follicles, replacing them with scar tissue. Unlike hair loss caused by hormonal changes or nutritional deficiencies, these conditions often present noticeable scalp symptoms such as redness, pustules, pain, or flaking before any visible hair loss occurs.
Lichen Planopilaris (LPP)
LPP is a chronic inflammatory condition thought to be autoimmune in nature. It causes patchy hair loss and noticeable scalp irritation in affected areas, which are often itchy, tender, or flaky.
- Autoimmune attack: Cytotoxic T-cells target stem cells in the follicle’s bulge area.
- Scalp inflammation: Lymphocytic infiltration around follicles leads to ongoing damage.
- Fibrotic scarring: Follicular structures are replaced with scar tissue, eliminating future hair growth.
- Irreversible loss: Once scarred, follicles cannot regenerate, resulting in permanent bald patches.
Dissecting Cellulitis of the Scalp (DCS)
DCS is a chronic, relapsing scalp disorder that causes deep nodules, abscesses, and sinus tracts filled with pus. It is most commonly seen in men, particularly those of African descent, but can affect others as well.
- Follicular blockage: Keratin buildup occludes the hair pore, trapping debris and bacteria.
- Acute inflammation: Follicular rupture triggers neutrophil-driven abscesses and pustules.
- Sinus tract formation: Deep nodules and interconnected tunnels develop under the scalp.
- Permanent follicle destruction: Repeated inflammation and healing by fibrosis result in permanent scarring alopecia.
Inflammatory scalp conditions, such as Lichen Planopilaris and Dissecting Cellulitis, are less prevalent in men compared to androgenetic or stress hair loss. However, they are often more aggressive and can result in permanent hair loss if not treated promptly. Early symptoms like painful bumps, scalp sensitivity, or unusual patchiness should never be overlooked. Seeking timely care from a dermatologist is crucial, but supplementing this with targeted scalp care can help protect unaffected follicles. Products like those from évolis, designed to inhibit FGF5 and support the hair cycle's growth phase, can be a valuable addition to a comprehensive routine aimed at strengthening existing hair and enhancing scalp health over time.
Stress Induced Hair Loss (Telogen Effluvium)
Stress is an unavoidable part of life for many of us, whether it stems from workplace demands, significant life events, or ongoing emotional challenges. Unfortunately, this stress can have a profound impact on the body, including its effect on your hair. Telogen effluvium is a temporary type of hair loss that happens when intense physical or emotional stress pushes a large number of scalp hairs into the resting (telogen) phase of their natural growth cycle prematurely. In men, this typically manifests as generalized thinning across the entire scalp, rather than in specific bald spots, and it usually becomes noticeable about 2–3 months after the stressful event. While this condition can be alarming, the good news is that it’s often reversible once the root cause of stress is identified and properly addressed.
How Cortisol Disrupts the Hair Growth Cycle
Cortisol, the body’s main stress hormone, plays a significant role in stress-induced hair loss. When stress becomes chronic, the hypothalamic-pituitary-adrenal (HPA) axis remains overactive, leading to persistently elevated cortisol levels.
This hormonal disruption impacts hair health in several key ways:
- Shortens the growth phase (anagen), reducing the time hair has to fully develop.
- Pushes hair follicles prematurely into the resting phase (telogen), resulting in noticeable hair shedding.
- Decreases keratin production, weakening the hair’s structure and resilience.
- Triggers inflammation and oxidative stress, which disrupts the health of the follicle environment and reduces healthy blood flow to the scalp.
Although these effects do not cause permanent damage to the follicles, they can hinder normal hair growth. Recovery is possible but often requires time, stress management, and targeted interventions.
Disruption of the HPA Axis Under Chronic Stress
When stress becomes chronic or poorly managed, the body's regulation of the hypothalamic-pituitary-adrenal (HPA) axis can falter. This dysregulation results in consistently elevated cortisol levels—the body's primary stress hormone—keeping the body in a prolonged state of alert. Over time, this disrupts crucial hormonal and cellular processes, including those that control the hair growth cycle.
The effects can be significant, particularly for men dealing with hair loss. Common issues include:
- Generalized thinning across the scalp, often more noticeable near the temples and crown
- Hair that becomes brittle and dry, increasing its susceptibility to breakage
- Slower regrowth, as the body prioritizes critical functions over less essential ones like hair production
Research indicates that men, much like women, are susceptible to telogen effluvium, a condition triggered by periods of severe physical or emotional stress. Common stressors include work-related burnout, major life transitions, recovery from illness, overtraining, and sleep disturbances. While it often takes a backseat to male pattern baldness, stress hair loss can occur independently or alongside it, potentially accelerating the appearance of thinning and making it more widespread.
What Sets Stress-Related Hair Loss Apart?
Stress-induced hair loss differs from genetic or hormonal types of hair loss in that it is usually temporary and not associated with follicle miniaturization. However, it can linger for months after the stressor has been resolved due to cortisol’s delayed impact on the hair growth cycle.
In men, stress-related hair loss often appears as:
- A sudden and excessive amount of shedding, typically occurring 2–3 months after a significant stressful event.
- A noticeable reduction in hair volume and density, especially when combined with pre-existing thinning.
- Persistent frustration, even when adopting a healthier lifestyle or reducing stress levels.
The solution to reversing this type of hair loss lies in rebalancing the body’s stress response and creating the necessary conditions for healthy hair growth to resume.
Tips for Supporting Hair Health During Stress
Addressing stress-related hair loss involves a holistic approach that both calms the nervous system and protects hair follicles from additional stress.
1. Regulate Cortisol and Calm the Nervous System
- Incorporate stress-relief practices such as meditation, deep breathing exercises, or gentle physical activities like yoga or walking.
- Ensure consistent, high-quality sleep to support optimal HPA (hypothalamic-pituitary-adrenal) axis function.
- Consult a healthcare professional about adaptogenic herbs like ashwagandha or rhodiola to help balance stress hormones.
2. Promote Scalp Health and Encourage Hair Growth
- Follow a nutrient-dense, anti-inflammatory diet rich in antioxidants, high-quality protein, and omega-3 fatty acids.
- Avoid harsh chemical treatments and excessive heat styling, as these can further damage hair follicles.
- Regularly care for your scalp to improve circulation and reduce inflammation at the surface.
3. Address FGF5 for Enhanced Recovery
Research indicates that stress may elevate levels of FGF5, a protein that signals hair follicles to transition out of the growth phase. By inhibiting FGF5, it may be possible to prolong the anagen (growth) phase, encouraging thicker and healthier regrowth.
Nutritional & Micronutrient-Related Hair Loss
When key essential nutrients like iron, vitamin D, and zinc are lacking, it can significantly affect men’s hair follicles—some of the fastest-growing tissues in the body. This deficiency may disrupt the growth phase (anagen), cause diffuse thinning, or even lead to telogen effluvium, a condition where numerous follicles prematurely enter the resting phase. The effects can become more pronounced when combined with genetic predispositions to male pattern baldness or heightened stress levels. Most men fail to recognize that they are experiencing nutritional deficiency hair loss because they tend to overlook the nutrients they consume on a daily basis. The good news is that this type of hair loss is often reversible by restoring optimal nutrient levels.
Iron Deficiency Hair Loss (Low Ferritin Levels)
Many men overlook the vital role of iron in maintaining healthy hair, despite its key function in oxygen delivery to follicle cells. Research reveals that nearly 45% of men with telogen effluvium (stress induced hair loss) have low ferritin levels, even in the absence of anemia. This deficiency weakens hair and accelerates shedding, particularly when hair loss has already begun.
Steps to take:
- Talk to your healthcare provider about checking your ferritin levels. Understanding your numbers is an empowering first step.
- If your levels are low, gently support your body by incorporating iron-rich foods or a supplement, paired with vitamin C to enhance absorption.
- Give your hair time and grace! Many men see stronger, healthier hair within 3–6 months of consistent care.
Vitamin D Deficiency Hair Loss
Vitamin D functions as a hormone, playing a crucial role in regulating hair follicles and supporting the immune system. Research indicates that men experiencing diffuse hair thinning or androgenetic alopecia often have insufficient vitamin D levels. A deficiency in this vitamin can extend the inactive phase of the hair growth cycle and delay regrowth after shedding.
What steps can you take?
- Ask your healthcare provider about getting your 25-hydroxyvitamin D levels tested. Consider supplementing with vitamin D3 if necessary, but always consult a healthcare professional for guidance.
- Maintaining healthy vitamin D levels can help regulate your hair cycle and alleviate stress on your hair follicles.
Zinc Deficiency Hair Loss
Zinc plays a crucial role in DNA and protein synthesis, both of which are vital for forming healthy hair shafts and supporting scalp health. Studies suggest that men experiencing male pattern baldness often exhibit lower zinc levels, which could influence how they respond to treatments.
Steps to take:
- Ask your healthcare provider about getting your serum zinc levels tested and correct any deficiencies through diet or supplementation.
- Avoid consuming excessive amounts of zinc (over 40 mg/day) to maintain a healthy balance with copper.
- Monitor for gradual improvements in hair thickness and strength over time.
The great news is that hair loss caused by nutritional deficiencies is often reversible, particularly when tackled early with a tailored approach. Collaborating with a healthcare professional to pinpoint specific nutrient deficiencies through blood tests is the most effective starting point. From there, making consistent dietary improvements, incorporating clinically appropriate supplements, and nurturing the hair follicle environment can foster optimal conditions for regrowth. A targeted hair wellness supplement—designed to deliver key vitamins and minerals in highly absorbable forms—can help create the internal foundation needed for stronger, healthier hair. Products like évolis’s Let There Be Hair not only support nutrient replenishment, but also complement follicle-focused solutions that work to extend the growth phase and ease hair cycle stress, offering a comprehensive path forward for men working to restore thickness and coverage.
Thyroid Hair Loss (Subclinical Hypo/Hyperthyroidism)
Thyroid imbalances, including subclinical hypothyroidism or hyperthyroidism, are often overlooked in men but can significantly impact hair growth. The thyroid gland plays a crucial role in regulating metabolism, hormonal balance, and cellular turnover throughout the body, including within hair follicles. When thyroid hormone levels are either too low or too high, it can disrupt the hair growth cycle, leading to diffuse thinning, excessive shedding, and slower regrowth. In men, this type of hair loss can initially appear subtle but may worsen over time if the imbalance remains untreated. Subclinical cases where thyroid levels are only slightly outside the normal range are particularly common and may present with minimal symptoms, such as fatigue, weight fluctuations, or changes in hair and skin health.
Thyroid Hair Loss in Men
Hair loss isn’t always caused by age or genetics—hormonal imbalances, particularly those related to the thyroid, can subtly disrupt the hair growth cycle. In men, thyroid issues are often overlooked or mistaken for male pattern baldness. However, even minor fluctuations in thyroid hormones can leave visible effects, such as thinner hair, slower growth, and excessive shedding.
The thyroid gland produces two essential hormones, T3 (triiodothyronine) and T4 (thyroxine), which play a vital role in regulating metabolism, energy production, and cellular turnover. Since hair follicles are among the most metabolically active structures in the body, they are especially sensitive to changes in thyroid hormone levels.
Even mild imbalances can alter the hair growth cycle over time, leading to weakened strands. Here are the most common outcomes:
- Shortened Anagen Phase: Growth slows down, and hair doesn’t reach its full length or thickness.
- Prolonged Telogen Phase: More hairs rest and shed than grow, leading to visible thinning across the scalp.
- Weakened Hair Structure: Hormonal deficits reduce keratin production, leaving strands brittle, dry, and breakable.
The Autoimmune Link: Hashimoto’s in Men
Hashimoto’s Thyroiditis is an autoimmune condition in which the immune system attacks the thyroid, resulting in persistent hypothyroidism. While it is more common in women, men can also experience this condition, and the underlying mechanisms of hair loss are identical for both.
Immune activity surrounding the thyroid prompts the release of cytokines, which are small proteins that serve as the immune system’s messengers and coordinate how cells respond to threats or maintain balance. In autoimmune hair loss (like alopecia areata), certain cytokines can mistakenly signal immune cells to attack healthy hair follicles which disrupt hair follicle signaling and compromise the immune privilege of the scalp. This leads to scalp inflammation, follicle miniaturization, and hair shedding, which can intensify during flare-ups or when hormone imbalances remain untreated.
How to Support Hair Growth During Thyroid Disruption
If thyroid dysfunction is contributing to hair loss, supporting the body holistically is key—alongside working with an endocrinologist for proper diagnosis and management:
- Nourish from Within: Focus on a whole-food, anti-inflammatory diet rich in zinc, selenium, iodine, and omega-3s to support both thyroid and follicle health.
- Regulate Autoimmunity: Reduce systemic inflammation with professional support, especially if autoimmune thyroid disease is diagnosed.
- Topical Follicle Support: Use formulas designed to improve circulation, strengthen the follicle, and reduce inflammation at the scalp level.
- Block FGF5 for Better Recovery: Elevated FGF5 is often seen in stressed follicles. Blocking this protein can help extend the growth phase and allow for denser regrowth—even when hair is under hormonal stress.
Hair loss in men is a complex condition with no universal solution. It’s shaped by various factors, including hormones, immune responses, inflammation, stress, and nutrition and effectively managing and potentially reversing hair loss begins with identifying its root cause. Whether it stems from DHT-driven androgenetic alopecia, thyroid-related shedding, or autoimmune and inflammatory scalp conditions, understanding the underlying biological processes is essential for taking informed, proactive measures.
Supported by the latest research, science-driven solutions like those from évolis focus on promoting follicle longevity, supporting the hair growth cycle, and inhibiting FGF5 for targeted results. These innovative, non-invasive strategies work alongside medical care to address hair health at its source. By nourishing your body from within and targeting the fundamental causes of hair loss, achieving lasting improvement is not just possible—it’s well within reach.
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At évolis, we care deeply about more than just your hair, we care about you. Your growth, confidence, and the life you envision for yourself are at the heart of everything we do!
Disclaimer: The information provided is for educational purposes only and does not constitute medical advice. These statements have not been evaluated by a medical professional. Always consult your physician or a qualified healthcare provider before making any medical decisions for yourself or others.